College football Week 1 picks against spread: Alabama or FSU? ncaa -football August 31, am EDT August 31, am EDT Sporting News picks. UCLA Bruins quarterback Josh Rosen (3) is pictured during the UCLA Bruins vs. the Texas A&M Aggies NCAA football game at Kyle Field in. USA TODAY Sports staff picks for the college football season kicks off NCAA Football: CFP National Championship-Clemson vs Alabama. This week's best bets for college football Week 1 include Alabama-FSU, Navy-FAU and Wyoming-Iowa. Pick: Alabama (-7). For picks from every Top 25 game from the CBS Sports staff, check out our Expert Picks page. Here are some score predictions for Week 1 of college football. The good news for Virginia Tech: it has the most trustworthy unit in this game. College football's opening weekend will attract bets from the average Joe to professional bettors for some of the biggest games. Florida State.